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PhD defence: Lixiang Jiang

α-synuclein in Parkinson’s disease: mechanistic significance of PLK-2/GSK-3β and Nrf2 antioxidant response

Info about event

Time

Friday 24 June 2022,  at 15:00 - 17:00

Location

The Blue Auditorium, Victor Albeck Building, Aarhus University and via Zoom

On Friday 24 June at 15.00, Lixiang Jiang defends her dissertation entitled "α-synuclein in Parkinson’s disease: mechanistic significance of PLK-2/GSK-3β and Nrf2 antioxidant response".

Parkinson's disease (PD) is the second most common neurodegenerative disease that affects the elderly population. Pathologically, accumulated α-synuclein is deposited as Lewy bodies or Lewy neurites in the dopaminergic neurons in the substantia nigra of the midbrain, leading to irreversible cell death and impaired dopamine release in the striatum. Nevertheless, to date, the underlying molecular mechanisms of PD development remain unclear and lack effective neuroprotective and neurorestorative therapies clinically to halt or slow disease progression. This PhD dissertation sought to investigate the underlying molecular mechanisms of PD development, which could potentially serve as a promising target to impede neurodegeneration in the PD brain.

The summary is written by the PhD student.

The defence is public and takes place in the Blue Auditorium, the Victor Albeck Building, Aarhus University and on Zoom. Please read the attached press release for more information.

Contact

PhD student Lixiang Jiang
Mail: lxj@biomed.au.dk 
Phone: (+45) 50336948

Read full press release