On Monday 5 June at 14:30, Maria Bisgaard Bengtsen defends her PhD dissertation entitled "Benign prostatic hyperplasia – management and long-term prognosis".

Benign prostatic hyperplasia is a prevalent condition in the ageing male population. It is a progressive disease with the risk of requiring surgery and developing complications. Acute urinary retention is a severe complication to benign prostatic hyperplasia associated with high mortality among men of all ages. In the mid-1990s, medical therapy for benign prostatic hyperplasia was introduced and rapidly replaced surgery as the first choice of treatment.

In this PhD thesis from Aarhus University, Health, containing four registry-based Danish studies, we examined the long-term effects of this shift in treatment and prognoses of benign prostatic hyperplasia and acute urinary retention. We described trends in the incidence and mortality of acute urinary retention in the era of medical therapy for benign prostatic hyperplasia. Furthermore, we examined whether treatment with 5-alpha reductase inhibitors reduced the risk of surgery and acute urinary retention in men with benign prostatic hyperplasia for up to 15 years of follow-up. Finally, we examined whether a first-time diagnosis of acute urinary retention was a marker of cancer.

The studies were preceded by a validation study, that examined the validity of the diagnostic coding of benign prostatic hyperplasia and acute urinary retention recorded in the Danish National Patient Registry.

The summary is written by the PhD student.

The defence is public and takes place in the auditorium at Department of Clinical Epidemiology, Olof Palmes Allé 43–45, 8200 Aarhus N. Please see the press release for more information.

Contact

PhD student Maria Bisgaard Bengtsen

Mail: mariabb@clin.au.dk

Phone: (+45) 22278988

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