Aarhus University Seal

PhD defence: Rasmus Reinke

Use of fluorescence in thyroid operations

Info about event

Time

Friday 21 June 2024,  at 15:00 - 17:00

Location

Aarhus University Hospital, Auditorium G206-142, Entrance G206

On Friday 21 June at 15.00, Rasmus Reinke defends his PhD dissertation entitled "Use of fluorescence in thyroid operations".

In total thyroidectomy, patients are at high risk of damage to either their parathyroid glands or their blood supply, which can result in low parathyroid hormone levels and a condition called hypoparathyroidism. Using fluorescence techniques, the parathyroid glands can be visualized during surgery, and their condition can be assessed. This PhD project investigates the value of fluorescence as an injection during surgery and the frequency of hypoparathyroidism caused by surgery in total thyroidectomy. Additionally, the consequences of hypoparathyroidism for patients in the long term are examined in national studies, including their kidney function and their risk of death compared to a matched background population.

Our results revealed a postoperative hypoparathyroidism rate of 16.6% in Denmark during the period from 1998 to 2017. Patients with hypoparathyroidism did not show increased mortality unless the surgical indication was cancer. However, both total thyroidectomy patients with and without hypoparathyroidism showed respectively 2-3 times higher risks of chronic kidney impairment over time compared to a matched background population. Fluorescence injections effectively predicted the risk of hypoparathyroidism when fluorescence intensity was low, facilitating the possibility of changing strategy during the surgery.

The summary is written by the PhD student.

The defence is public and takes place at Aarhus University Hospital, Auditorium G206-142, Entrance G206. Please see the press release for more information. 

Contact

PhD student Rasmus Reinke
Mail: rasrei@rm.dk      
Phone: +45 30364150

Read full press release