PhD defence: Ida Monrad Johannsen
Clinical and immunological factors associated with SARS-CoV-2 persistence in immunocompromised patients
Info about event
Time
Location
Conference room, D301-110+111 (32+33), Entrance D, Level 3, Aarhus University Hospital
On Friday 6 March 2026 at 14:00, Ida Monrad Johannsen defends her PhD dissertation entitled "Persistence of SARS-CoV-2 in Immunocompromised Patients: Immune Dysregulation, Viral Dynamics, and Clinical Implications".
Immunocompromised patients may experience prolonged or persistent SARS-CoV-2 infections. This project characterised and elucidated SARS-CoV-2 persistence in immunocompromised patients, related to viral dynamics, clinical, and host-intrinsic immunological factors. Clinical features and viral kinetics were characterised in a notable case of SARS-CoV-2 infection, persisting beyond 333 days in an immunocompromised host, displaying intra-host viral evolution. Clinical, serological, cellular, and transcriptional features associated with time to SARS-CoV-2 clearance were characterised in a prospective cohort of 42 patients. Overall, the findings indicate that viral persistence in a subset of immunocompromised patients is associated with an activation-related dysregulation of the anti-viral immuneresponse, rather than complete absence of immunity.
The summary is written by the PhD student.
The defence is public and takes place in Conference room, D301-110+111 (32+33), Entrance D, Level 3, Aarhus University Hospital. Please see the press release for more information.
Contact
PhD student Ida Monrad Johannsen
Mail: idamonrad@clin.au.dk
Phone: +45 41116204