PhD defence: Malene Kaasing Thomsen
Cerebral microcirculatory function and brain oxygenation in cognitively normal APOE-ε4 and APOE-ε3 carriers
Info about event
Time
Location
Auditorium G206-145, Aarhus University Hospital
On Friday 27 June at 14:00, Malene Kaasing Thomsen defends her PhD dissertation entitled "Cerebral microcirculatory function and brain oxygenation in cognitively normal APOE-ε4 and APOE-ε3 carriers".
New research reveals early brain changes in individuals with a genetic risk for Alzheimer’s disease.
Individuals with a genetic risk for Alzheimer’s disease show reduced oxygen metabolism and altered blood flow in the brain. This is demonstrated in a new PhD project from Aarhus University, providing insights into the early development of the disease.
Alzheimer’s disease is characterized by the accumulation of amyloid-beta and tau protein in the brain, and individuals carrying the APOE-ε4 gene variant have an increased risk of developing the disease. The PhD project has investigated how cerebral microcirculation and oxygenation differ in older adults without memory problems but with different APOE genotypes. The results point to early changes in brain metabolism and blood flow among APOE-ε4 carriers.
The summary is written by the PhD student.
The defence is public and takes place in Auditorium G206-145, Aarhus University Hospital. Please see the press release for more information.
Contact
PhD student Malene Kaasing Thomsen
Mail: Malenekaasing@cfin.au.dk
Phone: (+45) 50662442