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PhD defence: Maria Bolther Pælestik

Can specific ventilator settings or perioperative blood pressure improve outcomes for high-risk patients undergoing major surgery under general anesthesia?

Info about event

Time

Friday 27 March 2026,  at 14:30 - 16:30

Location

Auditorium J116-113, Entrance J, Sign J110, Aarhus University Hospital

On Friday 27 March 2026 at 14:30, Maria Bolther Pælestik defends her PhD dissertation entitled “Respiratory and hemodynamic targets during general anesthesia: addressing knowledge gaps in perioperative management”.

After surgery under general anesthesia, patients may develop complications that cannot be attributed solely to the surgical procedure itself. Optimization of perioperative management may therefore potentially reduce the risk of these complications.

This PhD project examined the existing evidence regarding the association between ventilator settings, perioperative blood pressure targets, and postoperative complications.
In addition, the project evaluated the feasibility of a factorial clinical trial involving interventions related to blood pressure targets and ventilator settings, including positive end-expiratory pressure (PEEP), tidal volume, and inspired oxygen fraction (FiO₂), in order to investigate how differences in these interventions influence the postoperative course.

The summary is written by the PhD student.

The defence is public and takes place in auditorium C114-101, Aarhus University Hospital, Entrance C. Please see the press release for more information. 

Contact

PhD student Maria Bolther Pælestik
Mail: marbolpe@rm.dk 
Phone: +45 93938240 

Read full press release