PhD defence: Maya Graham Noer
Invenstigation of potential new treatment options for acute myeloid leukemia
Info about event
Time
Location
Samfundsmedicinsk auditorium, building 1262, Aarhus University
On Friday 22 November at 14:00, Maya Graham Noer defends her PhD dissertation entitled "Generation of anti-FLT3 CAR T-cells by CRISPR/Cas9-editing for the treatment of Acute Myeloid Leukemia".
This new doctoral study has focused on developing a novel CAR T-cell therapy to treat acute myeloid leukemia (AML), a difficult to treat blood cancer. The research investigates a targeted approach using CRISPR gene-editing to engineer CAR T-cells that specifically recognize the FLT3 mutation, often found in relapsed AML cases.
The study compares CRISPR-based method with the more traditional virus based approach, aiming to create a more effective and stable CAR T-cell therapy. By integrating the CAR gene into a specific region of the T-cell DNA, the research seeks to improve therapy options for AML patients facing limited treatments.
This research adds to the growing field of precision immunotherapies and offers a promising step toward advancing leukemia treatment.
The summary is written by the PhD student.
The defence is public and takes place in Samfundsmedicinsk auditorium, building 1262, Aarhus University. Please see the press release for more information.
Contact
PhD student Maya Graham Noer
Mail: mp@clin.au.dk
Phone: +4541594922