On Friday 22 August at 13:00, Sarah Kelddal defends her PhD dissertation entitled "Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome".

Nephrotic syndrome is a kidney disorder that significantly increases the risk of developing blood clots (thrombosis). In a new PhD project from Aarhus University, Health, Sarah Kelddal, MD, has investigated the potential causes of this complication and how it might best be prevented.

The research showed that patients with nephrotic syndrome have increased thrombin generation, a key factor in blood clot formation, along with impaired ability to dissolve clots. one part of the study examined treatment with the anticoagulant apixaban to prevent thrombosis: Despite lower blood
concentratios in pateints with nephrotic syndrome, apixaban had the same anticoagulant effect as in healthy individuals. In an observational study, no patients receiving apixaban experienced a thrombosis while on treatment, suggesting efficient, prophylactic effect.

The summary is written by the PhD student.

The defence is public and takes place in Auditorium C114-101, Aarhus University Hospital. Please see the press release for more information. 

Contact

PhD student Sarah Kelddal
Mail: kelddal@clin.au.dk
Phone: (+45) 78450000

Read full press release