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PhD project

Neuromodulation of restless legs syndrome: exploring mechanisms and treatment strategies

Call for applications for a fully financed PhD fellowship

Project description

Restless legs syndrome (RLS) is a neurological sensory-motor disorder. The pathogenesis is unknown, and today, only symptomatic treatment is available. This study aims to investigate the neural mechanisms underlying RLS using novel neurophysiological methodologies and to evaluate the neuromodulatory effects of biomarker-directed therapeutic repetitive transcranial magnetic stimulation (rTMS), transcranial static magnetic stimulation (tSMS) and transcutaneous spinal direct current stimulation (tsDCS) in reducing disease disability in RLS. This study will investigate the pathophysiology of RLS and explore the short-term therapeutic effects of these three different neuromodulation modalities which are suggested to reduce cortical and spinal hyperexcitability. The effects of these modalities on clinical scales, threshold tracking TMS parameters, navigated TMS cortical mapping, brainstem and spinal reflexes will be investigated.

The PhD student will be part of an active research environment with expertise in clinical neurophysiological techniques. 

Qualifications

Candidates must have a master´s degree. Candidates must have an interest in neuroscience.  A degree in biomedical engineering is preferred, as is experience in neuroscience and in the analysis of neurological and health data. The candidate must master English.

How to apply

Please submit your application via this link. Application deadline is 25 August 2026 at 23:59 CET. Preferred starting date is 1 October 2026.

For information about application requirements and mandatory attachments, please see our application guide 

Further information

Please contact Professor Hatice Tankisi, hatitank@rm.dk, for more information.

All interested candidates are encouraged to apply, regardless of their personal background. Salary and terms of employment are in accordance with applicable collective agreement.