Call for applications for a fully financed PhD fellowship

Project description

The Project

The project aims to characterize the biological and pharmacological effects of the investigational drugs perampanel and senicapoc in GBM patients. The PhD candidate will integrate clinical trial work with advanced molecular profiling and pharmacokinetic analyses to understand treatment response and resistance.

The project includes:

• Clinical trial participation, including patient interaction and follow-up

• Collection and processing of patient-derived tissue, CSF, and blood samples

• Molecular and cellular profiling (e.g., single-cell RNA sequencing and biomarker analyses)

• Pharmacokinetic and pharmacodynamic analyses of CNS drug penetration

• Functional studies on living tumor tissue and drug responses

• Biobanking and structured sample handling workflows

• Integration of clinical, molecular, and pharmacological data

Your Tasks

As a PhD student, your tasks will include both clinical and experimental work in a highly collaborative environment:

• Participation in clinical trial operations, including screening, inclusion, and monitoring of patients

• Collection, handling, and processing of human tissue and biofluids

• Registration and validation of data in electronic databases (e.g., REDCap/eCRF)

• Participation in regulatory, administrative, and GCP-related tasks

• Coordination of biobanking and sample logistics

• Contribution to multi-omics analyses (e.g., scRNA-seq, molecular profiling)

• Participation in pharmacological analyses and drug profiling

• Collaboration with national and international partners

• Scientific dissemination (publications and conference presentations)

We offer

• A unique translational PhD project at the interface of clinic and laboratory

• Direct involvement in a first-in-field clinical trial

• Access to advanced multi-omics and pharmacological platforms

• A strong international research environment with leading collaborators

• Training in both clinical trial conduct and experimental techniques

Supervision

You will be supervised by Associate Professor Anders Rosendal Korshøj and work closely with collaborators across Aarhus University Hospital and international partner institutions.

Qualifications

Your profile

Required qualifications:

• Master’s degree in medicine, biomedicine, molecular biology, neuroscience, pharmacology, or a related field
• Strong interest in translational and clinical research
• Ability to work with human samples and patient-related research
• Excellent organizational and communication skills
• Fluency in English (written and spoken)

Preferred qualifications:

• Experience with clinical research and/or clinical trials
• Knowledge of Good Clinical Practice (GCP)
• Experience with molecular laboratory techniques or omics technologies, such as snRNA-seq, spatial molecular profiling, genomics, and/or epigenetic profiling
• Familiarity with data handling and database systems (e.g., REDCap)
• Experience with bioinformatics, pharmacology, or drug analysis is an advantage

Personal competencies:

• Motivated and capable of working independently
• Strong collaborative skills in multidisciplinary settings
• Structured and detail-oriented approach to both laboratory and clinical tasks
• Interest in combining patient interaction with experimental research

How to apply

Please submit your application via this link. Application deadline is 27 May 2026 at 23:59 CET. Preferred starting date is 1 July 2026.

For information about application requirements and mandatory attachments, please see our application guide.  

Further information

Please contact Associate Professor Anders Rosendal Korshøj, anders.r.korshoj@clin.au.dk, for more information.

All interested candidates are encouraged to apply, regardless of their personal background. Salary and terms of employment are in accordance with applicable collective agreement.